The first direct freight train arrived in Barking, London, from Yiwu in Zhejiang province, China, which opens new opportunities for trade and investment for post-Brexit UK. The One Belt One Road (OBOR) provides possibilities for enhancing partnerships for sustainable growth, high-tech manufacturing, investments in knowledge and skills development, and global value chains between China, UK and countries along the New Silk Road. This study presents possibilities. http://sticerd.lse.ac.uk/textonly/india/research/outputs/NewSilkRoadUKchinaOBOR.pdf